Thousands of workers all over the world are affected with the outbreak of covid-19 virus especially in clothing and textile industries. This paper illustrates the challenges facing clothing and textile workers during post covid-19 pandemic. The common jobs handled by clothing and textile workers are sewing, ironing, packing and lifting heavy loads which are monotonous, continuous and prolonged. This paper indicates that working for a long period without rest, absence of personal protective equipment and inadequate provision of ergonomic facilities at workplace leads to major health-related issues such as musculoskeletal, cardiovascular respiratory, neurological, nutrition and mental health problems among clothing and textile workers. It was recommended that government should provide adequate equipment that will enable clothing and textile workers to work with little effort. Keywords: Health, Challenges, Clothing and Textile, Workers, Post covid-19 pandemic