This study investigated the possible effects of the combination of two most commonly used imported artificial food seasonings used in many delicacies during occasions/events in the South Eastern part of Nigeria on the liver and kidney function. Twenty (20) wistar albino rats were assigned to four groups (A,B,C and D) of five animals per group. The combined seasonings (coded - BM) was administered in graded doses; group A(Control), group B(200mg/kg), group C(400mg/kg) and group D(800mg/kg). The study lasted for two weeks and BM was administered once daily through oral intubation. The animals were anaesthetized with chloroform and sacrificed on the 15th day. Blood samples were collected by cardiac puncture into plain tubes for analysis after an overnight fast. Alanine aminotransferease(ALT), aspartate aminotransferase(AST) and alkaline phosphatase(ALP) were determined spectrophotometrically using enzymatic methods. Urea and creatinine levels were evaluated using Berthelot and Jaffe Slot